Genetic Disorders in Pembroke Welsh Corgis

Genetically inherited diseases occur in Corgis like any other dog and as genetic work continues new disorders will be identified.  All of our adult breeding dogs are genetic tested through Embark.  Embark breeders panel tests for over 200 genetic canine diseases including the genetic diseases that affect Pembroke Welsh Corgis.  DM, EIC and vWD1 are simple genetic diseases found in Corgis where other diseases such as hip dysplasia and IVDD are more complex and have both a genetic and environmental component. 

DM - Degenerative Myelopathy

Degenerative Myelopathy (DM) is a neurological disorder that affects the spinal cord.  It begins around age 10 with weak muscles in the rear legs and progressively gets worse until the dog is paralyzed.  Dogs fall into one of the following categories.  Affected dogs inherit the gene for the disease from BOTH parents.  Not all dogs who carry two copies of the gene actually develop the disease.  Carriers are dogs with only one copy of the gene and can NOT develop the disease.  Symptoms begin late in life around 10 years of age with an unsteady wobbly gait. As the disease progresses the rear legs become weak and eventually the dog is unable to walk.  Responsible breeders test their breeding adults and do not make matings which might result in puppies who could develop the disease. We test all our dogs for DM and plan matings so puppies do not develop DM.

 

Clear       

These dogs do not have a copy of the DM gene.   They will NEVER develop the disease and can not pass DM on to their offspring.  

Carrier      

These dogs inherited one copy of the DM gene and a copy of the normal gene. They will NEVER develop this disease but can pass the DM gene on to its offspring 50% of the time. 

Affected      

These individuals have two copies of the DM gene.   This dog may or may not develop the disease during its lifetime but it is at risk of developing DM later in life.  These individuals will always pass one copy of the DM gene on to its offspring therefore they must be bred to DM clear individuals.  

VWD1 - Von Willebrand's Disease

Von Willebrand’s Disease (vWD1) is a blood clotting disorder found in multiple breeds of dogs.  It may cause prolonged bleeding after an injury and bruising. There are multiple mutations that cause the disease in dogs.  Pembroke Welsh Corgis can be affected by the type 1 mutation which is the mildest form and they MUST inherit the gene for the disease from BOTH parents to be affected.  Carriers are dogs with only one copy of the gene and can NOT develop the disease.  Symptoms include abnormal bleeding, bleeding gums, blood in feces or urine, nosebleeds and easy bruising. Responsible breeders test their adults and do not make matings which might result in puppies who could develop the disease.  We test all of our dogs for vWD1 and plan matings so puppies do not develop vWD1.

Clear       

These dogs do not have a copy of the mutated vWD1 gene.   They will NEVER develop the disease and can not pass vWD1 on to its offspring.  

Carrier      

These dogs carry both a copy of the normal gene and a copy of the vWD1 gene. They will NEVER develop this disease but can pass the mutated gene on to its offspring 50% of the time. 

Affected      

These dogs have two copies of the vWD1 gene.   These individuals will be affected by the disease and will always pass the vWD1 gene on to its offspring.  

EIC - Exercise Induced Collapse

Exercise Induced Collapse (EIC) is a disease where dogs lose control of their muscles following periods of extreme exercise.  Dogs with this disorder become wobbly 5-25 minutes after extreme exercise and may collapse and even die if exercise is continued. Affected dogs inherit the gene for the disease from BOTH parents.  Carriers are dogs with only one copy of the gene and can NOT develop the disease.  Symptoms normally show up between 5 months to 3 years of age.  Most attacks last 5 to 25 minutes but some dogs die immediately after an attack.  Thankfully exercise regimes can be altered and these dogs can lead long normal lives.  Responsible breeders test their adults and do not make matings which might result in puppies who could develop the disease. We test all of our dogs for EIC and plan matings so puppies do not develop EIC.

Clear       

These dogs do not have a copy of the mutated EIC gene.   It will NEVER develop the disease and can not pass EIC on to its offspring.  

Carrier      

These dogs carry both a copy of the normal gene and a copy of the EIC gene. They will NEVER develop this disease but has a 50% chance of passing the EIC gene on to its offspring. 

Affected      

These dogs carries two copies of the EIC gene.   They are at risk of an EIC attack and will always pass the EIC gene on to its offspring.  

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Harman Corgis Watermark Long LLC

Phone:  Leslie 806-202-2076
               Wayne 806-202-2175

Email: Leslie@harmancorgis.com

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