Genetic diseases with simple modes of inheritance
Progressive Retinal Atrophy (PRA-rcd3)
What is PRA-rcd3?
This genetic disease causes blindness.
What are the symptoms?
Puppies are normally diagnosed by the time that they are 8 weeks old. They develop night blindness first then total blindness by 1 to 4 years of age.
Is there a treatment?
There is no treatment.
Genetic testing & our breeding program
We test ALL of our breeding dogs for PRA-rcd3
We have no dogs who carry genes for this disease.
What genetics are involved?
The gene involved is PDE6A on chromosome 4.
This disease is a recessive autosomal genetic disease (like vWD1 and EIC) meaning that for a dog to be affected it must inherit 2 copies of the mutation (one from each parent).
